Different recommendations for daptomycin dosing over time in patients with severe infections.
نویسندگان
چکیده
TO THE EDITOR—We thank Sachdev et al for their interest in and evaluation of our article [1]. The respondents present data from a survey of providers in metropolitan areas with the highest human immunodeficiency virus incidence, and their results complement and support our findings. Unlike our article, which specifically surveyed infectious disease physicians, the respondents captured responses from primary care providers. Their results demonstrate that provider self-efficacy and normative beliefs about preexposure prophylaxis (PrEP) were associated with intention to prescribe PrEP. These data build on our findings that complex and multiple barriers exist to the provision of PrEP among both infectious disease specialists and primary care providers. In addition, their work supports our conclusion that multifaceted approaches will likely be necessary to the successful provision of real-world PrEP.
منابع مشابه
Considerations for higher doses of daptomycin in critically ill patients with methicillin-resistant Staphylococcus aureus bacteremia.
BACKGROUND Higher daptomycin doses are advocated for select methicillin-resistant Staphylococcus aureus (MRSA)-related infections, but the probabilities of target attainment (PTA) and toxicity of these doses have not been characterized in critically ill patients. METHODS We evaluated the plasma pharmacokinetics (PK) and clinical outcomes of a cohort of critically ill patients treated with dap...
متن کاملA Prospective Study to Assess Vancomycin Serum Concentrations in Pediatric Patients with Current Dosing Guidelines
Concerns about increasing bacterial resistance to vancomycin, have caused the adult treatment guidelines to recommend higher trough concentrations based on the type and location of infectious disease. Although these recommendations are not specific to children, the values can be extrapolated. This prospective study was designed to evaluate efficacy of current vancomycin dosing recommendations t...
متن کاملA Prospective Study to Assess Vancomycin Serum Concentrations in Pediatric Patients with Current Dosing Guidelines
Concerns about increasing bacterial resistance to vancomycin, have caused the adult treatment guidelines to recommend higher trough concentrations based on the type and location of infectious disease. Although these recommendations are not specific to children, the values can be extrapolated. This prospective study was designed to evaluate efficacy of current vancomycin dosing recommendations t...
متن کاملSafety of high-dose daptomycin in patients with severe renal impairment
Background Treatment options are limited for infections due to multidrug-resistant Gram-positive pathogens. Daptomycin is a lipopeptide antibiotic with concentration-dependent killing characteristic and dose-dependent post-antibiotic effect. To achieve optimized pharma-codynamic effect, some experts advocated using a high dose of daptomycin (≥9 mg/kg) for severe infections. However, the safety ...
متن کاملInvasive Aspergillosis in COVID-19: A Review Study and Recommendations for Diagnostic Approaches
Background and purpose: COVID-19 is an emerging viral disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Bacterial or fungal superinfections of the lung may cause complications in clinical manifestations, treatment, and increase the mortality rate. In this article, we reviewed previous studies on invasive aspergillosis (IA) in viral infections and in adjustment with...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
دوره 58 12 شماره
صفحات -
تاریخ انتشار 2014